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CDC HIV/STD/TB Prevention News Update

Thursday, March 9, 2000
The CDC National Center for HIV, STD, and TB Prevention provides the following information as a public service only. Providing synopses of key scientific articles and lay media reports on HIV/AIDS, other sexually transmitted diseases and tuberculosis does not constitute CDC endorsement. This daily update also includes information from CDC and other government agencies, such as background on Morbidity and Mortality Weekly Report (MMWR) articles, fact sheets, press releases, and announcements. Reproduction of this text is encouraged; however, copies may not be sold, and the CDC HIV/STD/TB Prevention News Update should be cited as the source of the information. Contact the sources of the articles abstracted below for full texts of the articles.

Peer-Review Headlines

General Meadia


Peer-Review Headlines

Estimation of Completeness of AIDS Case Reporting in Massachusetts

Epidemiology (www.epidem.com) (03/00) Vol. 11, No. 2, P. 209; Jara, Michele M.; Gallagher, Kathleen M.; Schieman, Scott
Researchers from the Massachusetts Department of Public Health and the Massachusetts Division of Health Care Finance and Policy attempted to estimate the completeness of AIDS case reporting in Massachusetts. In January 1993, the Centers for Disease Control and Prevention expanded its AIDS case definition to include HIV-infected individuals who have less than 200 T cells and three clinical conditions. The change in definition resulted in a 100 percent increase in reported AIDS cases nationwide in 1993 and a 201 percent increase in cases reported in Massachusetts compared to the previous year. The Massachusetts researchers sought to analyze the impact of the definition change in relation to AIDS case reporting to the state, comparing cases with regard to sex, race, and mode of HIV transmission. Using data from the 1994 Massachusetts Uniform Hospital Discharge Data Set, the researchers concluded that the state AIDS registry was 92.6 percent complete; the Medicaid claims dataset indicated that the AIDS registry was 94.5 percent complete. Unreported AIDS was more common among women, and AIDS cases with a history of injection drug use were also at greater risk for being unreported when compared to cases involving infection via male with male sex. Overall, the researchers note that the completeness of AIDS reporting in Massachusetts is high, although differences by gender and mode of HIV transmission remain.


General Media

2 Gene Therapy Studies Halted

Washington Post (www.washingtonpost.com) (03/09/00) P. A7; Weiss, Rick; Nelson, Deborah
Researchers at St. Jude Children's Research Hospital in Memphis have suspended two more gene therapy experiments in light of fears that cells being injected into children with cancer may be infected with HIV or hepatitis. The genetically engineered cells were formed from the master batch of cancer cells that were tested for viruses a few weeks ago, after another experiment was thought to be contaminated. Paula Bowman, who is coordinating the three studies, noted that while the master batch was tested, she has not been able to verify that later generations of cells were also screened. Bowman immediately notified the Food and Drug Administration (FDA) after reviewing the program and finding possible contamination of the neuroblastoma cells. Of the 42 children treated with the engineered cells, 21 are still living, but none show direct evidence of infection. Bowman said, however, that none of the patients have been tested specifically for infection. The FDA continues to investigate the errors leading to the initial contamination scare, even though the cells were not infected.

Taking Care of Those Who Take Carnival Too Far

"Taking Care of Those Who Take Carnival Too Far" New York Times (www.nytimes.com) (03/09/00) P. A4; Gonzalez, David
Carnival is a time of hard-earned restraint for many in Trinidad who do not want to return to old addictions. Steve Richards, who runs Rebirth House, a drug rehabilitation program, tries to help people maintain the 12 steps of recovery, particularly during the festive Carnival season, which celebrates with dancing, singing, and drinking. Also, at the Port of Spain General Hospital, Dr. Joseph Olowe notes, "During Carnival there is a high incidence of being free sexually." Concerns about possible HIV infection and unwanted pregnancies spurred public health group to prepare for the celebration with an education campaign titled, "Sex? Latex!" Rebirth House urges its members to stay away from drinking or drug buddies as they resist the urge to crowd into the streets and take part in the festivities.

Teens Report Pressure to Have Unprotected Sex

Reuters Health Information Services (03/08/00)
A new survey from by the Washington-based National Campaign to Prevent Teen Pregnancy shows that almost half of U.S. teens say that pressure by a partner has led them to engage in unprotected sex. Using data from three national youth surveys involving thousands of young people, the researchers found that while most of the teens said that birth control is necessary for every sexual encounter, three out of 10 girls questioned said they used no contraception the last time they had sex. Many teens cited drug and alcohol use as reasons for neglecting contraception during sex. The researchers note that education is important for teens who have sex, as is parental guidance, particularly for younger teenagers.

National Network on AIDS Study

Houston Chronicle Online (www.chron.com) (03/08/00); Hopper, Leigh
Baylor College of Medicine, Texas Children's Hospital, Harvard, Stanford, and several other leading research groups are joining together for a new national network to study treatments for serious childhood illnesses. Dr. David Poplack, head of the Texas Children's Cancer Center, believes the combined resources will stimulate faster research. Paul Glaser, chairman of the foundation board, said that because the study of HIV has helped in the study of other diseases, the group will expand its focus to include more areas of research. The Elizabeth Glaser Pediatric AIDS Foundation, which was established in 1988 to raise funds for pediatric HIV/AIDS research, is supporting the effort with $8 million.

No Compensation for Infected Blood

"No Compensation for Infected Blood" BBC News Online (www.news.bbc.co.uk) (03/07/00)
The British government has decided not to compensate hemophiliacs who were infected with hepatitis C through tainted blood products. Over 4,000 people were infected during the 1970s and 1980s. While another 1,200 people who contracted HIV from contaminated blood products received compensation, health minister John Denham said that hemophiliacs with hepatitis C will not receive special payments, and no public inquiry is necessary. "The needs of people whose conditions result from inadvertent harm is met from benefits available to the population in general," Denham said. Conservative MP Michael Mates opposed the decision, noting that some hepatitis patients have had to stop working because of their illness.

U.N. Peacekeepers Spreading AIDS, U.S. Says

"U.N. Peacekeepers Spreading AIDS, U.S. Says" United Press International (03/08/00); Baker, Ashley
Some United Nations peacekeepers are "unintentionally" spreading HIV in the countries they are trying to help, according to Richard Holbrooke, the U.S. ambassador to the United Nations. Holbrooke asserted, "As long as I am ambassador, the United States will never again vote for a peacekeeping resolution that does not require specific action by the (U.N.) to prevent AIDS from spreading by or to peacekeepers." Lawmakers are trying to gain support for a $100 million trust fund that, over the course of five years, would be used to fight AIDS in sub-Saharan Africa, India, and the former Soviet Union.

AIDS Threatens to Kill 10 Percent of South African Miners

PANA Wire Service (03/08/00); Mulenga, Mildred
New statistics show that 10 percent of South Africa's 500,000 mine workers could die from AIDS unless aggressive measures are taken. According to Marlea Clarke, a researcher from the University of Cape Town, AIDS-related deaths are increasing for miners, who often visit commercial sex workers. Clarke reported that more than three-quarters of the sex workers living in informal settlements near some of the mines were infected with HIV. Clarke, who reported her findings at the Regional Labor Migration Seminar for Southern Africa, said that many of the HIV-infected workers were also infected with tuberculosis.

Injection Fears [in Pakistan]

"Injection Fears [in Pakistan]" New Scientist (www.newscientist.com) (02/19/00) Vol. 165, No. 2226, P. 5
A recent report suggests that some healthcare workers in Pakistan may be transmitting hepatitis C virus (HCV) via contaminated injections. Researchers from Aga Khan University in Karachi studied 74 HCV-infected individuals in Hafizabad. According to the report, published in the journal Epidemiology and Infection, the patients were 12 times as likely to have had at least four injections a year compared to uninfected individuals in their households.

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